Quote:
Originally Posted by patns
Oh dear on my spelling Linden, i couldn't understand why I was getting all that clock info. I'll try that again but spelled correctly this time!
Pat
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I had a friend years ago who used to say that bad spelling was a Scottish national trait. I have no idea where she came up with that idea, but if the shoe fits. It sure does in my case.
Here is a very, very useful article. I think it's in the public domain so I'll quote it. Long but so valuable. Well, shoot. The links didn't transfer. But you can see what it's all about. For the article Google Sam Snyder low carb Eades Paleo. Updated 12.26.11.
Dr. Michael Eades and the Science of Low Carb and Paleo Nutrition
Posted on October 21, 2010
Dr. Michael Eades is the co-author of many books on nutrition which he wrote with Dr. Mary Dan Eades. They were some of the first physicians to collect research on low carbohydrate & paleo nutrition, explain the biochemistry behind the effectiveness of low carb diets, and apply it to helping patients lose weight in a bariatric medicine practice.
I recently went through all of the tweets published by Dr. Michael Eades over the last few years to locate research studies that indicate the efficacy of low carbohydrate nutrition and diets that emulate those of early humans. Eating meat led to the development of larger brains and jumpstarted human evolution. Before the advent of agriculture, early human beings were stronger than modern people and lived longer than expected. If hunter-gatherers somehow had access to modern medicine (antibiotics, emergency medicine, etc.) they would likely have lived as long or longer than modern people. Theres also some discussion of this in the first chapter of the book The Protein Power Lifeplan.
Since these papers are from the last few years, they represent a small fraction of the research behind low carbohydrate and paleo nutrition. Nevertheless, they provide an interesting look at one of the most exciting areas of nutrition. In this post I specifically focus on the health benefits associated with low carb and paleo diets rather than the dangers of sugar and grain, which are described in detail by bloggers listed in Low Carb and Paleo Diet Links. Besides, one frightening study by itself (Fructose induces transketolase flux to promote pancreatic cancer growth) is reason enough to give up sugary things.
I found the titles of the papers that were tweeted by Dr. Eades and then put links to them on PubMed.
Here are the low carb and paleo studies:
A 6-Month, Office-Based, Low-Carbohydrate Diet Intervention in Obese Teens. (Link)
A Diet High in Meat Protein and Potential Renal Acid Load Increases Fractional Calcium Absorption and Urinary Calcium Excretion without Affecting Markers of Bone Resorption or Formation in Postmenopausal Women. (Link)
A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer Initiation. (Link)
A low-carbohydrate diet may prevent end-stage renal failure in type 2 diabetes. A case report. (Link)
A low-protein diet exacerbates postprandial chylomicron concentration in moderately dyslipidaemic subjects in comparison to a lean red meat protein-enriched diet. (Link)
A Pilot Study of the Spanish Ketogenic Mediterranean Diet: An Effective Therapy for the Metabolic Syndrome. (Link)
A randomized controlled trial on the efficacy of carbohydrate-reduced or fat-reduced diets in patients attending a telemedically guided weight loss program. (Link)
A Randomized Trial of a Low-Carbohydrate Diet vs Orlistat Plus a Low-Fat Diet for Weight Loss. (Link)
A Very Low-Carbohydrate Diet Improves Gastroesophageal Reflux and Its Symptoms. (Link)
A Very Low-Carbohydrate Diet Improves Symptoms and Quality of Life in Diarrhea-Predominant Irritable Bowel Syndrome. (Link)
Acid diet (high-meat protein) effects on calcium metabolism and bone health. (Link)
Adiponectin Changes in Relation to the Macronutrient Composition of a Weight-Loss Diet. (Link)
Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study. (Link)
Beneficial impact on cardiovascular risk profile of water buffalo meat consumption. (Link)
Brain fuel metabolism, aging, and Alzheimers disease. (Link)
Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice. (Link)
Cancer incidence in vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford). (Link)
Carbohydrate for weight and metabolic control: Where do we stand? (Link)
Carbohydrate restriction (with or without additional dietary cholesterol provided by eggs) reduces insulin resistance and plasma leptin without modifying appetite hormones in adult men. (Link)
Carbohydrate restriction favorably alters lipoprotein metabolism in Emirati subjects classified with the metabolic syndrome. (Link)
Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet. (Link)
Carbohydrate Restriction, as a First-Line Dietary Intervention, Effectively Reduces Biomarkers of Metabolic Syndrome in Emirati Adults. (Link)
Change in Food Cravings, Food Preferences, and Appetite During a Low-Carbohydrate and Low-Fat Diet. (Link)
Changes in weight loss, body composition and cardiovascular disease risk after altering macronutrient distributions during a regular exercise program in obese women. (Link)
Combined effects of saturated fat and cholesterol intakes on serum lipids: Tehran Lipid and Glucose Study. (Link)
Comparison of high protein and high fiber weight-loss diets in women with risk factors for the metabolic syndrome: a randomized trial. (Link)
Dietary cholesterol and the risk of cardiovascular disease in patients: a review of the Harvard Egg Study and other data. (Link)
Dietary Composition and Nonalcoholic Fatty Liver Disease. (Link)
Dietary intake of saturated fatty acids and mortality from cardiovascular disease in Japanese: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC) Study. (Link)
Dietary intake of α-linolenic acid and low ratio of n-6:n-3 PUFA are associated with decreased exhaled NO and improved asthma control. (Link)
Dietary ketosis enhances memory in mild cognitive impairment. (Link)
Dietary predictors of 5-year changes in waist circumference. (Link)
Diets with High or Low Protein Content and Glycemic Index for Weight-Loss Maintenance. (Link)
Effect of a low glycemic index compared with a conventional healthy diet on polycystic ovary syndrome. (Link)
Effect of a relatively high-protein, high-fiber diet on body composition and metabolic risk factors in overweight women. (Link)
Effect of ketogenic mediterranean diet with phytoextracts and low carbohydrates/high-protein meals on weight, cardiovascular risk factors, body composition and diet compliance in Italian council employees. (Link)
Effect of short-term low- and high-fat diets on low-density lipoprotein particle size in normolipidemic subjects. (Link)
Effect of the carbohydrate counting method on glycemic control in patients with type 1 diabetes. (Link)
Effect of weight loss by a low-fat diet and a low-carbohydrate diet on peptide YY levels. (Link)
Effects of a Diet Higher in Carbohydrate/Lower in Fat Versus Lower in Carbohydrate/Higher in Monounsaturated Fat on Postmeal Triglyceride Concentrations and Other Cardiovascular Risk Factors in Type 1 Diabetes. (Link)
Effects of a high-protein, low-carbohydrate v. high-protein, moderate-carbohydrate weight-loss diet on antioxidant status, endothelial markers and plasma indices of the cardiometabolic profile. (Link)
Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial. (Link)
Effects of a Low Carbohydrate Weight Loss Diet on Exercise Capacity and Tolerance in Obese Subjects. (Link)
Effects of a popular exercise and weight loss program on weight loss, body composition, energy expenditure and health in obese women. (Link)
Effects of a whey protein supplementation on intrahepatocellular lipids in obese female patients. (Link)
Effects of dietary carbohydrate restriction versus low-fat diet on flow-mediated dilation. (Link)
Effects of Dietary Coconut Oil on the Biochemical and Anthropometric Profiles of Women Presenting Abdominal Obesity. (Link)
Effects of dietary fat modification on oxidative stress and inflammatory markers in the LIPGENE study. (Link)
Effects of whey protein isolate on body composition, lipids, insulin and glucose in overweight and obese individuals. (Link)
Efficacy and Safety of a High Protein, Low Carbohydrate Diet for Weight Loss in Severely Obese Adolescents. (Link)
Egg consumption as part of an energy-restricted high-protein diet improves blood lipid and blood glucose profiles in individuals with type 2 diabetes. (Link)
Eggs distinctly modulate plasma carotenoid and lipoprotein subclasses in adult men following a carbohydrate-restricted diet. (Link)
Enhanced weight loss with protein-enriched meal replacements in subjects with the metabolic syndrome. (Link)
Evidence that protein requirements have been significantly underestimated. (Link)
Gastrointestinal transit, post-prandial lipaemia and satiety following 3 days high-fat diet in men. (Link)
Gluconeogenesis and energy expenditure after a high-protein, carbohydrate-free diet. (Link)
High protein diets decrease total and abdominal fat and improve CVD risk profile in overweight and obese men and women with elevated triacylglycerol. (Link)
High protein intake reduces intrahepatocellular lipid deposition in humans. (Link)
High-protein diet promotes a moderate postpartum weight loss in a prospective cohort of Brazilian women. (Link)
High-protein low-carbohydrate diets: what is the rationale? (Link)
High-Protein Weight Loss Diets and Purported Adverse Effects: Where is the Evidence? (Link)
Higher Branched-Chain Amino Acid Intake Is Associated with a Lower Prevalence of Being Overweight or Obese in Middle-Aged East Asian and Western Adults. (Link)
Increased adipose tissue lipolysis after a 2-week high-fat diet in sedentary overweight/obese men. (Link)
Increased Consumption of Dairy Foods and Protein during Diet- and Exercise-Induced Weight Loss Promotes Fat Mass Loss and Lean Mass Gain in Overweight and Obese Premenopausal Women. (Link)
Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. (Link)
Insulin Sensitivity as a Mediator of the Relationship Between BMI and Working Memory-Related Brain Activation. (Link)
Ketogenic diets: An historical antiepileptic therapy with promising potentialities for the aging brain. (Link)
Limited Effect of Dietary Saturated Fat on Plasma Saturated Fat in the Context of a Low Carbohydrate Diet. (Link)
Long-term outcomes of children treated with the ketogenic diet in the past. (Link)
Low carbohydrate ketogenic diet prevents the induction of diabetes using streptozotocin in rats. (Link)
Low-carbohydrate diet induced reduction of hepatic lipid content observed with a rapid non-invasive MRI technique. (Link)
Low-Carbohydrate Diet Review: shifting the paradigm. (Link)
Low-Carbohydrate Diets and Prostate Cancer: How Low Is Low Enough? (Link)
Measures of postprandial wellness after single intake of two proteincarbohydrate meals. (Link)
Meat consumption and cooking practices and the risk of colorectal cancer. (Link)
Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. (Link)
Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type diet. (Link)
Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report. (Link)
Moderate-carbohydrate low-fat versus low-carbohydrate high-fat meal replacements for weight loss. (Link)
Optimal dietary approaches for prevention of type 2 diabetes: a life-course perspective. (Link)
Palmitic acid in the sn-2 position of triacylglycerols acutely influences postprandial lipid metabolism. (Link)
Prevention and reversal of diet-induced leptin resistance with a sugar-free diet despite high fat content. (Link)
Protein choices targeting thermogenesis and metabolism. (Link)
Protein-enriched meal replacements do not adversely affect liver, kidney or bone density: an outpatient randomized controlled trial. (Link)
Protein, amino acids and the control of food intake. (Link)
Red meat from animals offered a grass diet increases plasma and platelet n-3 PUFA in healthy consumers. (Link)
Reduced Body Weight and Adiposity With a High-Protein Diet Improves Functional Status, Lipid Profiles, Glycemic Control, and Quality of Life in Patients With Heart Failure: A Feasibility Study. (Link)
Reduced Pain and Inflammation in Juvenile and Adult Rats Fed a Ketogenic Diet. (Link)
Relationships of maternal zinc intake from animal foods with fetal growth. (Link)
Renal Function Following Long-Term Weight Loss in Individuals with Abdominal Obesity on a Very-Low-Carbohydrate Diet vs High-Carbohydrate Diet. (Link)
Reversal of Diabetic Nephropathy by a Ketogenic Diet. (Link)
Saturated fat, carbohydrate, and cardiovascular disease. (Link)
Saturated Fats: A Perspective from Lactation and Milk Composition. (Link)
Schizophrenia, gluten, and low-carbohydrate, ketogenic diets: a case report and review of the literature. (Link)
Short Report: Relationship between Quality Protein, Lean Mass and Bone Health. (Link)
Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction. (Link)
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimers disease: a randomized, double-blind, placebo-controlled, multicenter trial. (Link)
Suppressive effect of short-chain fatty acids on production of proinflammatory mediators by neutrophils. (Link)
Testing Protein Leverage in Lean Humans: A Randomised Controlled Experimental Study. (Link)
The anabolic response to resistance exercise and a protein-rich meal is not diminished by age. (Link)
The Beneficial Effects of a Paleolithic Diet on Type 2 Diabetes and Other Risk Factors for Cardiovascular Disease. (Link)
The effect of a low-fat, high-protein or high-carbohydrate ad libitum diet on weight loss maintenance and metabolic risk factors. (Link)
The effect of low-carbohydrate diet on left ventricular diastolic function in obese children. (Link)
The Effect of Protein and Glycemic Index on Childrens Body Composition: The DiOGenes Randomized Study. (Link)
The Effects of Consuming Frequent, Higher Protein Meals on Appetite and Satiety During Weight Loss in Overweight/Obese Men. (Link)
The influence of creatine supplementation on the cognitive functioning of vegetarians and omnivores. (Link)
The Influence of Higher Protein Intake and Greater Eating Frequency on Appetite Control in Overweight and Obese Men. (Link)
The ketogenic diet for the treatment of glioma: Insights from genetic profiling. (Link)
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma. (Link)
The myocardial contractile response to physiological stress improves with high saturated fat feeding in heart failure. (Link)
Therapeutic role of low-carbohydrate ketogenic diet in diabetes. (Link)
Weight and metabolic outcomes after 2 years on a low-carbohydrate versus low-fat diet: a randomized trial. (Link)
Updated 12/26/2011