11 Sucralose Side Effects

11 Sucralose Side Effects

There are some sucralose side effects that may cause you to think twice about using the sweetener. Sucralose is sold as a sugar substitute known as Splenda and is 600 times sweeter than table sugar. The product Splenda contains no calories and does not cause an insulin boost. The product has even begun replacing aspartame. The FDA reviewed studies in human beings and animals and found that sucralose did not pose any carcinogenic, reproductive, or neurological risk to humans.

Sucralose is a synthetic compound, which is basically sugar that has been modified by adding chlorine atoms. Chlorine is added to many products and does not necessarily make the product dangerous. On the other hand, consuming chlorine is not advised in large amounts. This synthetic compound is created when sugar is treated with trityl chloride, acetic anhydride, hydrogen chlorine, thionyl chloride and methanol in the presence of dimethylformamide, 4-methylmorpholine, toluene, methyl isobutyl ketone, acetic acid, benzyltriethylammonium chloride and sodium methoxide, which makes it unlike anything else found in nature.

Digesting Sucralose

Once sucralose becomes ingested it goes largely unrecognized by the body as food, which is why it has no calories. Most people don’t absorb a significant amount of it in their small intestine--only 15% by most accounts. Ironically, your body will try to clean unrecognizable substances by digesting them, so it is very likely that the healthier your gastrointestinal system is the more you’ll absorb the chlorinated molecules of sucralose.

The Side Effects of Sucralose

The sweetener has been implicated as the cause of many side effects, including:

  • Skin Rashes/Flushing
  • Panic-like Agitation
  • Dizziness and Numbness
  • Diarrhea
  • Swelling
  • Muscle aches
  • Headaches
  • Intestinal cramping
  • Bladder issues
  • Stomach pain

 There have been no long-term studies of the side effects of sucralose in humans, but the Splenda manufacturer’s own short-term studies showed that very high doses of sucralose shrank thymus glands, enlarged livers, and caused kidney disorders in rodents. The doses were measured at a level far beyond what would be expected in an ordinary diet.

Splenda contains more than just sucralose when it is sold at your local stores–it’s made with dextrose, and sometimes with maltodextrin, neither of which were included in the original studies of sucralose. The evidence of side effects associated with sucralose is accumulating slowly. Most of the testing is funded by the food industry, which has an interest in the outcome. One thing is certain. Some of the chemicals that comprise this artificial sweetener are known to be hazardous.

  • Ray Nicholson

    How in the world can they tell if an animal is having chest pain, depression or any of the other syptoms mention? Another thing is what are the most reason sudies for humans? If this product can cause memory lost if used in like energy drinks?

  • A Ro

    Ray, the article states “short-term studies showed that very high doses of sucralose shrank thymus glands, enlarged livers, and caused kidney disorders in rodents.” The other symptoms mentioned were linked to people who actually had those side effects from consuming sucralose. It’s important to read an article clearly and fully so that we don’t start a chain reaction of misinformation.

    I’m not sure if this product can cause memory loss, but I do know that aluminum does. Aluminum is found in the packaging of many types of food and drinks. It’s also found in deodorant and is currently being sprayed in the air as a means of “bioengineering,” along with other heavy metals.

  • Russell

    i was just diagnosed type 2 betic a couple months ago. I immediately stopped consuming all sugar, and trying different sweeteners. The best one i like is stevia. But was having to settle for sucralose in a lot of the diabetic products. I started to have real bad leg pain, painful skin in hairy areas, so my dr immediately put me on amyltriptiline. seemed like it wasnt working. There was some real bad days, and some hardly any pain. I just figured it was to to my job, being on my feet all day sometimes. well, just a couple days ago, on a day off, i ate 5 or 6 sugar free fudge bars(splenda sweetened) over the course of the day. That night was the worst nite i could remember. now yesterday, i didnt consume any sucralose, and my leg pain was almost not there. thats when i started to make the correlation, so just for an experiment, i ate the last fudge bar this morning, and 10 minutes later, i had that all too familiar muscle pain in my legs.

  • Carolyn

    I’m the only person in my family that’s not diabetic. But I’m also the only one who exercises, watches what I eat and don’t eat any of the artificial sweeteners including SPlenda. I used stevia, but had to be careful about using too much and it being bitter. So I found this product called Newsweet and it works good. I can bake and use my normal recipes, just replace the sugar with Newsweet. No more stomach issues nor diahrea either. I think you can only buy Newsweet online.

  • Kate

    It would be great if those who experienced effects also detailed how much they ate of the Splenda/Sucralose. If you have a side effect and can make the correlation like Russell did I have to recommend making a complaint to the FDA as well as writing the manufacturer of the product and even the HQ of the grocery store where you purchased it. Sad to say but they don’t know what they don’t know.

    Personally I’m a purist really and have used Stevia for years, through trial and error I like the liquid form only and the NOW or KAL brands with no aftertaste. I also choose only honey, agave or real maple syrup for other options depending on the use. There is a new sweetener out now that has good info and use called Lakanto. For diabetics I’d like to encouage more protein in your diets (veggies have quite a bit) like using Whey protein shakes excellent trial done which in fact proved that DIET is the problem/answer not prescriptions. Don’t be afraid of the health food store, go and ask questions, get a great book by many wonderful authors like, Dr Young, Jordan Rubin, Dr Ray Strand and others. Do not rely on your Dr to heal you, he is not God and you are responsible for You. No one else controls what you feed You. Only one body for One life so take care of it…Jack Lalane and his wife knew it a long time ago and proved it is possible.

  • John P. Adams

    I read a report on Splenda (a year or so back) that claimed it to cause memory loss and it killed something in the gut essential for a good functioning immune system, and seemed to not return after being off of it for two weeks. The study was done on rats. There was, also, mention of infertility in the male rats after just a couple weeks of a certain dose. Though, I’m not certain as to the site that I read this on, I felt confident that it was reputable. I’m sure that it can still be found if someone was to research it. I have NO faith in the FDA… That’s for certain!

  • Gayle

    A few years ago I was having headaches and severe joint pain and just thought the joint pain was a really bad case of arthritis. My elbow would hurt so bad that some nights I couldn’t sleep. My mom watched a show and told me other people were having some of the same problems and thought it was because of Splenda (sucralose). I stopped using Splenda and within a week my symptoms were gone, just plain gone. Just the other day I had a tblspoon of sugar free dressing and by that night my legs and arms hurt so bad I couldnt make it up my steps standing up. Guess what was in that dressing. Splenda! I will not touch the stuff now!

  • luke

    after looking up sucralose a few different ways… Wikipedia in my opinion gave the best information on the stuff..

    the bad thing i found is even if you avoid artificial sweeteners you will most likely still consume them through something else you buy because it does something like increases shelf life. :) the bad things said about sugar were worse and the lists longer, aspartame is rated worse then sucralose, i wonder if the problems with sucralose are mostly because chlorine is involved in making the stuff?! the list of chemicals used to make sucralose is CRAZY, but a good thing about it is that most of it is not digested by the body at all. i just started trying the stuff, just as a break from sugar, not as a replacement, i say all sweeteners are sugars and all have similar side effects… it simply takes way less sucralose then it does sugar to sweeten something… another bad thing about sucralose is it does something to kill certain good bacterias.

  • Anonymous314159265358979323

    While this article starts out well by explaining the chemistry of sucralose, it ends up being a non-informative article. Table salt contains clorine (sodium cloride), yet is perfectly safe in reasonable amounts; and the danger comes, not from the clorine in table salt, but from the sodium in excessive table salt intake.

    The studies so far say sucralose is safe; and trying to scare everyone without controlled studies showing proof of harm is a real dis-service to the public.

  • bob

    If you know so much how about you spell chlorine right

  • Janet Hrechka Dorkin

    Everyone makes typos!