I've been on it for a little over a month. Generally it helps, but there was one night that i felt crazy for some reason. I had repeated anxiety attacks and felt out of control. I think that may have been due to drinking an extreme amount of caffeine that night- I had been a designated driver, and was drinking diet coke and tea all night, which I never have caffeine anymore.
The main problem I have with zoloft is, er, the side effects caused in the bedroom, if you knwo what I mean. But, my hubby's on zoloft too, so we're both a-struggling.