I can do a lot more physically. At my highest, it was painful to have to stand for more than 5 minutes at a time (walking was more tolerable, it was the standing still that would make my legs ache terribly). I was slow and lumbering. You know those fold-up tables with the attached benches that a lot of grade school cafeterias have? I worked an after school program and had trouble sitting with the kids. Theater seats were a problem. My asthma got pretty fierce (I thought I had outgrown it but it came back when I got over 300 lbs). I had trouble getting up off the floor, or even out of chairs at times, come to think of it. I was always, always completely and utterly exhausted. I had no agility, no balance. And I couldn't buy jeans off the rack even from a plus sized specialty shop, so I stopped wearing them altogether.
I'm far from my goal weight, but I can walk and stand without issue, and can even run/jog for short distances (although it's something that needs a lot of work yet). I haven't tried sitting at one of those fold-up tables in years but I'm willing to bet I'd be fine now, as I am in theater seats. My asthma has gotten much better and I have high hopes it will go away like it did when I was younger. I can get off the floor easily now, although it's not the most comfortable place for me to sit yet, lol. I'm not tired all the time, in fact I feel like I have a decent amount of energy (still room to improve there). I feel more agile and able as I move around, doing every-day things. Oh, and I'm small enough to buy jeans off the rack at Old Navy (they only go up to a size 20).
The changes are small and slow, but they certainly add up. I can bend and move again. I can squat to pick something dropped on the floor without a second thought, when I used to loathe having to reach for something on the bottom shelf of the fridge. It's been good to feel more able, and I can only imagine it gets better from here. The thing is that it's such a slow change that it may be easy to not notice at all.