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My experience has been that you can lose 3 lbs. a week in the beginning. The more weight you have to lose, the more of a calorie deficit you can have each week, while still eating heathfully.
I strongly recommend that you don't set weekly loss goals. I have found that the scale doesn't cooperate! Whenever (in the past) I set scale goals and didn't meet them, I felt like a failure - whcih pretty much sabotaged my efforts and ended my weight loss.
This time around, I just set eating and exercise goals. That way, when I ate perfectly on plan (POP) and the scale didn't budge for two solid weeks, I didn't get upset.
You CAN do this - and really - in the scheme of things - will it matter how many weeks it took to lose the weight?