I usually take my vitamins "with food". Meaning I will have some of my shake, take a couple of vitamins, have a few more sips of shake, take a couple more, etc...
The only time I have ever had a problem with vitamins is if I take them on a completely empty stomach.
I also second that you need to make sure you are getting quality vitamins. Look for vitamins in a "vegetarian capsule". Your system can break down the capsule much easier than a tablet (like an asprin or Centrum vitamins) and you only get a small percentage of the vitamin. Blue Bonnet, Sol-Ray, Rainbow light, Garden of Life are a few very good options for quality vitamins in capsule form.
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