Hi, I have been on prednisone for 4 yrs. now. My dose is lowered now. I don't have any increase in wrinkles from the lowering of the prednisone. My moon face is now gone. You can hit the link for my pic's if you'd like. It will show the difference in how I've changed with the wt. loss. I really think that the lowered prednisone dosage has helped in my wt. loss and maintenance efforts. I now take 20 mg. on even days, 10 mg. on odd days. I used to take 40 and 60 mg. on alternate days. Good luck and I hope you're able to wean off the prednsione, that is what my Dr. is trying to do with me.
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