I think alot depends on your health issues. Some people get depression relief from Lamictal. I understand it often requires a rather high dosage. There is a small chance of a rather problematic rash associated with Lamictal. I have not heard of people gaining weight on this medication. I have heard it referred to as "weight neutral." However, everyone is different. My guess is that most folks either don't gain weight or gain a very tiny bit.
On the other hand, people seem to either remain steady (neutral) on Topamax or LOSE weight on this medication. However, Topamax has some annoying side effects. One of which has to do with memory loss. Sort of like big time ADD. If your work requires a good memory, you might want to either keep your dosage low or not take it at all. Or another thought would be to combine Topamax with an antidepressant of some sort...ideally, something weight neutral.
BTW, I have been posting a lot about how sometimes the B vitamins help a little with depression. Same with Fish Oil.
Wishing you well.
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