I've tried nearly every pill I could get my hands on, including Xenical.
IMO, no pill is going to work more than very short term. It's just not worth it. It messes with your body and does nothing to establish healthy eating habits. For long-term success, the only answer I know is finding a healthy eating plan that you can stick with for life and a healthy lifestyle to go with it.
There just aren't any easy answers.
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