Studies have show that when combined with diet and exercise, people seem to lose 6 pounds more annually (and that's if taking the higher dose prescription drug Xenixal) when compared with controls who diet and exercise without alli.
Does it work? Yes. It's mechanism of action is to inhibit pancreatic lipase in the gut and therefore inhibit breakdown of fatty acids so that you excrete them without digestion.
Is it worth it? Probably not. For a few extra pounds yearly, you are exposing yourself to a possible risk (there has not been enough long term studies on potential risk factors), dealing with the awful side effects (flatulence, oily stool), and paying a decent amount for the pills. Very few physicians would recommend it but few would discourage you from it if you really insist.
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