Look at your eating and exercise, first. I think once you get on plan, you'll lose weight.
Maybe it is periomenopause, but I don't think hormones account for everything. I have PCOS and have been able to lose weight just fine. But I'm carb sensitive and I've had high blood glucose readings.
I have cut out most non vegetable carbs from my diet. I avoid sugar, bread, pasta, rice, potatoes, etc. It's sounds kind of boring, but I love my fish, eggs, milk and salads.