I'm sorry this has you down. Although I cannot give you ample advice with what you've been through, I can support you on your journey.
I, too, work from home. I have my own Etsy business that started off as a hobby. With a lot of drive and passion I made it a successful full time job and I decided to do the same with my weight loss. I believe you can do the same. When you started your jewelry business it was small steps right? A sale here.. A sale there..., right? You can do take this same route with losing weight and getting on the right path.
I'm here if you need a buddy - I'm just at the beginning of my journey, but I can relate on how hard it is to get this damn thing going.
Good luck