I agree with those who suggest you take it slowly with jogging/running. I did C25K about four years ago when I was about 275 lbs, but I thought I was doing it slowly enough that it would be okay. I had been doing low-impact aerobics and walking tapes for a while. I would re-do many of the c25K weeks because I wasn't ready to move to the next week's plan. But I was doing it!
I didn't finish the whole program, and never did a 5K run. About ten weeks into it, my ankle began giving me grief, and I went back to walking. Soon, I couldn't do much at all. Now I have achilles tendinitis, and some days it's all I can do to get down the seven steps from my bedroom floor to the living room floor in my home. I have to do ankle stretches every day, and I can't remember the last day I haven't been at least a 2 on the pain scale (of 1 to 10). Most mornings or after I get up after sitting a while it's about a 4 or 5, and as I warm up it gets down to a 3 or 2.
I still walk, after taking a complete exercise break (other than stretching). I'm up to 30-45 minutes now, which would have been impossible this time last year without a handful of Ibuprofen. And I definitely have to start out very slowly when I begin my walks.
That being said, I don't want to discourage you from exercise... just be aware of what you are doing and how your body is reacting. You may be much younger and healthier than I was, and you've lost more weight than I did before I tried c25k.
there are a lot of fun videos out there that are more exciting than Sansone and may better fit your energy and interest level. Look at
collagevideo.com for the absolutely best selection. They allow you to select by beginner, intermediate, and advanced... low impact or high... style (dance, calisthenics, resistance training)... and even by instructor. And they have great reviews and allow you to preview most of the videos before you buy.