IS anyone taking any supplements or herbs to help with weight loss?

I do have to credit AM-300 to my 50 pound weight loss so far. I have really tried so many and am very lucky that this one has stuck with me and worked for me this long. I never had the first negative effect from it and it has kept me at a good pressure. I have heard that some people actually have a higher pressure while on supplements such as this. I never had a whole lot of success with a few others.