Hi all! I've been trying to read through the many threads and posts here to find out more about Sarafem (aka Prozac). I've been prescribed a 14 day regimen for severe PMS, and I've only been taking it for three months and have put on 10 pounds so far. Yikes! Has anyone else dealt with this and if so, what did you do? I feel like I'm not eating/drinking more than I used to.
I've always exercised and haven't decreased my activity either. I'm ready to quit taking it if I'm going to gain this much and there's nothing I can do about it.

Oh my I feel your pain!!! I was on fluoxetine (also generic Prozac) for about 3 months and gained 10 pounds as well, AND felt completely lethargic with no energy all the time.

I just recently switched to Wellbutrin (and by recently, I mean 3 days ago) but already I feel like I have a bit more energy. Could be the placebo affect, but I'll take it! I chose Wellbutrin because it has a lower incidence of weight gain and sexual side effects, but I don't know anything about its treatment for PMDD. We'll see how it does with the weight issue.

Good luck to you!! I think you should definitely talk to your doc about other options. PMDD sucks, and so does gaining weight! There has to be a better answer for you.