I disagree. Some studies have shown that HFCS bypasses your body's indicators letting you know when you are getting full/satisfied. It has to do with the way it is digested -- it's digested differently than glucose.
http://www.drmirkin.com/nutrition/3021.html
But to answer your original question: from what I understand, the term "corn syrup" can vary between countries. In Canada, we have some "corn syrups" that contain glucose. So, your body would digest part of it in a similar manner to that of other glucose-sugars (table sugar, for instance). HFCS, on the other hand, is highly processed. It bypasses all natural means of our bodies' way of saying "stop! that's enough, I'm full".