So far doing the speed/hill workouts has felt fine. This morning I ran 10 miles and didn't make it back in time to do the speed workout. Most of the people on my running team are not doing the long run first. It's a practical thing for me. The two workouts happen to be on the same day and I have a choice whether or not to do them.
Right now here is my workout schedule:
Monday -- strength
Tuesday -- 3 mile run with running team, 45 minutes indoor cycling class, 3 mile walk (I'd love to drop the walk, but the dog needs it)
Wednesday -- 5 mile run, strength
Thursday -- 3 mile run with running team, 45 minute indoor cycling class, 3 mile walk
Friday -- strength
Saturday -- rest
Sunday -- long run (currently 10 miles), sometimes speed or hills as well