Splenda (Sucralose) vs. Aspartame: Which Is Worse?

When it comes to sugar substitutes, splenda and aspartame are the two big players in the game. Aspartame was discovered in 1965 as a by-product of an anti-ulcer drug. Splenda is a relative new comer which was discovered in 1976 and is made by adding maltodextrin or dextrose to “bulk” it up. Both splenda and aspartame are fine white powder and are available in packets varying in size from handheld packets to five pound bags, so you can get just what you need to sweeten your tea or bake your pies.


Splenda is used in about 4,000 different foods and drinks, and since it is nearly 600 times sweeter than sugar, a little bit goes a long way. Splenda has the added advantage of being stable when heated so it can be used in baking and still retain its sweetness. However, in recipes that it put on top of it does not created the same texture as sugar so it does not work as well in recipes like creme brulee.


Aspartame is used in about 6,000 different foods and drinks (from supplements to soft drinks) currently on the market. Aspartame has phenylalanine in it, so people who have a rare genetic disease called pheylketonuria must avoid it. In addition, aspartame does break lose its sweet flavor when it is heated so it is not recommended for use in baking. Also, in things like hot cocoa, there can be a bitter taste if it is left to set awhile.


Splenda has shown no adverse reactions in testing until the amount consumed was equal to 4,000 packets a day. Aspartame has been a bit more controversial because there have been questions about the validity of the research done in the past. However, more than 90 different countries have found aspartame to be safe for human consumption. As late as 2007, a safety evaluation concluded that aspartame is safe to use as a sweetener with no nutritious value.


While both splenda and aspartame sweeten the foods they are added to, there are some people who report a bitter taste left in their mouths after eating foods made with aspartame. Splenda has no reported aftertaste and can be used spoonful for spoonful just like table sugar. In most restaurants splenda (usually in little yellow packets) is readily available, while aspartame (most often in pink packets) not being around as much.


When deciding between splenda and aspartame, it its important to remember that studies conclude that both are safe when consumed within reasonable limits. However, for baking, splenda wins hands down. In prepared items you may need to taste the foods to decide if you are one of those who gets an unpleasant taste left in your mouth after eating aspartame items.

With the aspertame testing controversies resolved it now boils down to personal preference and the way you intend to use splenda or aspartame that can help you decide which one is right for you.


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  • Laura

    Actually, Aspartame is usually found in blue packets. Pink packets are generally saccharin. There was one product that released Aspartame in pink packets, but this was a one-time special and they’ve since reverted back to blue.


  • E. Fisher

    I will explain why Aspartame is so dangerous: When the temperature of this sweetener exceeds 86 degrees F, the wood alcohol in ASPARTAME converts to
    formaldehyde and then to formic acid, which in turn causes metabolic acidosis. Formic acid is the poison found in the sting of fire ants. The methanol toxicity mimics, among other conditions, multiple sclerosis and systemic lupus.

    Many people were being diagnosed in error. Although multiple sclerosis is not a
    death sentence, Methanol toxicity is!

    Systemic lupus has become almost as rampant as multiple sclerosis, especially with Diet Coke and Diet Pepsi drinkers.

    The victim usually does not know that the Aspartame
    is the culprit. He or she continues its use; irritating the lupus to such a degree that it may become a life-threatening condition. We have seen patients with systemic lupus become
    asymptotic, once taken off diet sodas.

  • P H

    Go to this website for move information.


    Or better yet, sit back and enjoy a movie about it!

  • P H

    Aspartame: Sweet Misery A Poisoned World

  • S. Morris

    There is plenty of fear mongering going around concerning sucralose. Created as a pesticide? Causes abdominal cramps? Releases gaseous chlorine in your body? None of these have any validity but are quoted ad nauseum to sell books.

    If there were proof of negative effects, you should be able to find the proof on the internet. Instead you just find people saying “studies show” without actually naming the studies. There are no studies, just writers who are selling sensational, but not factual, books.

    Your body does not break down sucralose. If you don’t brush your teeth after drinking a sucralose sweetened beverage you will have a sweet aftertaste in your mouth for hours because not even the bacteria in your mouth can break it down.

    If you have intestinal discomfort after eating food sweetened with Splenda, look for Maltitol or other sugar-alcohols in the list of ingredients. Splenda does not cause intestinal discomfort. But many Splenda-sweetened foods also contain sugar-alcohol sweeteners which cause bloating and a variety of uncomfortable intestinal issues.

    My personal experience with sucralose is that I have enjoyed it since it first became available in the US. I successfully lost 19% of body weight in 3 months on a diet where I used Splenda-brand sucralose instead of sugar. Splenda is great for cooking, it just doesn’t caramelize.

  • morris

    not only has aspartame been shown to cause weight gaain ,but it is 10%methanol which is wood alcahol methanol is converted to formic acid (formaldehide ) aspartame is the only food with methanol that has no ethanol which is what doctors use to treat methanol poisoning which the estamated lethal dose 10% at roughly two teaspoons there are only 2 other ingredients in aspartame aspartic acid and phenalanine ,phenalanine is used in the production of dopamine when phenalanine is consumed in this form it doesnt go thru the 12 hour digestion and absorbtion process it goes straight to the brain this means it kills brain cells and in higher doses would be a legal alternative tto caffeine cocaine and meth

  • Max

    There are plenty of studies showing many harmful effects of both sucralose and aspartane. So while your comment “studies conclude that both are safe”, may be true in that some studies support this, there are many studies that find the opposite. Try Google! For me, I will just avoid both as well as sugar and stick to water for drinking.

  • Beck Mason

    Aspartame yuck, if they say it’s not harmful they are talking out their arses

  • Solarcide

    Sucralose always leaves a bad taste in my mouth for hours after I eat anything that has it as an ingredient. Aspartame does as well. Surely I can’t be alone in this.