The charts are definitely a generalization. Most people use the %max method, that you and the other posters are talking about but the ACSM teaches a much more accurate method that takes your individual resting heart rate into consideration. This is the Karvonen method. I dont know your stats so i'll just show you mine and you can do this on your own

Take your resting heart rate before you get out of bed in the morning to get the most accurate reading. Whenever you calculate your target heart rate for exercise, you need a range, not just a number.
220-20=200bpm (my max heart rate)
55-(My resting heart rate; RHR)
200-55(RHR)=145 (my heart rate reserve; HRR)
145*.65=94.25+55(RHR)=149.25 bpm (the low end of my range, 65%)
145*.85=123.25+55(RHR)=178.25 bpm (the high end of my range, 85%)
So when I do cardio, my personal target heart rate range is 149.25-178.25 bpm.
When deciding on your precentages that you want to work out at, be honest with yourself and your fitness level. I workout everyday so 65-85% is okay for me but someone who doesnt feel they are as fit or is just starting out is much safer working their heart at about 50-70%.
If you workout at too high of a percentage, your body begins to work anaerobically instead of aerobically and cannot sustain this high of an intensity.
As for your, whats the best way to workout question..thats a whole larger topic and it comes down to preference more than anything.
If you have any other questions feel free to ask. I'm a health sciences major and i'm about to sit for my personal training certification and I can talk about exercise for hours haha