Just to throw my $0.02 in - A few months ago, my doctor and I finally decided to try Metformin to combat my insulin resistance. She said, "It's not a miracle, but it'll probably help you lose some weight."
I didn't end up having any of the sickness many folks report at all, no matter when I took it, or with whatever food (or no food at all). I felt pretty good, maybe a little less tired. I did, however, gain 16 pounds in three weeks, all the while actually eating
better than I had been before I was taking the meds. I didn't change my diet drastically - I just figured I'd help the medication along by trying to cut out some junk like soda and candy. At first, I thought the extra weight might just be bloating, but as the scale kept creeping up, I panicked, and my doctor and I decided it was best to stop once we hit the three-week mark and the scale was still shooting rapidly upward.
The moment I stopped taking the pills, I stopped gaining weight. I became pretty bummed out by the "failure" and even slipped into some bad dietary habits afterward, and I've
still lost a couple of those pounds since then, so I have little choice but to blame the medication.
She did say my experience was very unusual, so I guess it's just my luck!
