Quote:
Originally Posted by Spinymouse
From the publication: the receptors were detected in human duodenal biopsy or by postmortem samples and detected by immunofluorescence; confirmed by cells immunostained, laser-captured and subjected to RT-PCR.
Feeding studies were done.
Natural sugars used in the study were glucose and sucrose. There was also a non-metabolizable nonsweet sugar (2-deoxy-glucose) used as a control which did not cause the GLP-1 release as did the natural sweetners and the sucralose.
I'm still wading through it all!
jo
Wow, it's amazing how "Greek" a lot of that is to me. But after reading it a couple of times, it sounds like they are doing feeding studies (on animals only?) to find out which substances cause the GLP-1 secretions. So it was glucose and sucrose as well as sucralose...
And were the human studies just done to find the receptors? Or were the feeding studies on humans too!
And that non-metabolizable nonsweet sugar (2-deoxy-glucose) ... it may not cause the secretions, but do we want to eat it????
Seriously, thanks for wading through this stuff!