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Old 04-14-2018, 07:33 AM   #1
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Default Blood Tests WORSE when dieting.

Everyone seems to suggest that dieting will improve my blood test results but, for the second time now, when I have been

1. dieting and
2. fasting over 12 hours...

I have had bad lipid results. A few years ago I was dieting and fasting and my LDL came back at 220. My doctor freaked and wanted to put me on meds. We had my VLDL tested and it showed that the vast majority of the LDL was the LARGE particles that were considered not to be dangerous. But the next time I had my cholesterol tested and I wasn't fasting it went down to 158. It is about that every time I get it tested when I am either not dieting or not fasting.

Recently I did the same thing (fasting and dieting) and .. same result.

Anyone know why?
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Old 04-14-2018, 08:03 AM   #2
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I have heard of this, but I don't know why it happens. Since I am on statins, I cannot really relate to it. I believe it is not the same for everyone. Dieting/fasting improves blood work for some, and worsens it in others. I think I read that results can get worse when you first start out, but improve as you continue on. I am not telling you to ignore your doctor's advice, just giving my opinion on why.
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Old 04-14-2018, 08:44 AM   #3
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I am not telling you to ignore your doctor's advice, just giving my opinion on why.
Ha, I am fine with ignoring my doctors advice. Again this time she wanted to put me on meds but I told her no and explained the issue. You can see it on my blood work. Fasting blood work is much more likely to cause a high LDL. Frankly I also find it makes my blood sugar worse --but the result was still low. 90.

My sister has this same issue so I am presuming it is genetic.

Someone once suggested that your body is put under stress when your not getting enough food LDL is one of the ways your body deals with stress. This makes me wonder if I should be getting my lipids done in the afternoon. I would say 95% of my lipid tests are either fasting or after a small breakfast.
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Old 04-14-2018, 09:13 AM   #4
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So I might have found it.

DEHYDRATION

Dehydration during fasting increases serum lipids and lipoproteins.
https://www.ncbi.nlm.nih.gov/pubmed/7895421

I have always had trouble staying hydrated during dieting and fasting. Even if I drink water I tend to use the facilities more.
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Old 04-14-2018, 09:42 AM   #5
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Originally Posted by AnnRue View Post
So I might have found it.

DEHYDRATION

Dehydration during fasting increases serum lipids and lipoproteins.
https://www.ncbi.nlm.nih.gov/pubmed/7895421

I have always had trouble staying hydrated during dieting and fasting. Even if I drink water I tend to use the facilities more.
Great detective work, Ann!! You may have hit the nail on the head! I have a tendency to get dehydrated, since I hate having to run to the bathroom so much. Because of a recent medical development I have been instructed to limit my fluids, but they didn't really tell me what that means. How much is too little and how much is too much. I will have to put that on my list of questions for my next doctor's appointment.
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Old 04-14-2018, 10:05 AM   #6
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Now I really wonder what result it would make for my cholesterol tests. I have 99% of those tests early morning. Right after coffee. Even if I have breakfast and am not dieting it is likely that I am not as fully hydrated as I might be if I had the tests later in the day. Frankly I am not at all sure if I have even ever had a cholesterol test past 12 PM.
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Old 04-14-2018, 10:14 AM   #7
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My doctor insists that all my cholesterol testing is fasting, with no coffee, only water. As soon as I arrive at the lab they ask if I fasted, and I don't think they would test if I didn't. But it sounds like the hydration is important.
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Old 04-14-2018, 12:08 PM   #8
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My doctor insists that all my cholesterol testing is fasting, with no coffee, only water. As soon as I arrive at the lab they ask if I fasted, and I don't think they would test if I didn't. But it sounds like the hydration is important.
You should mention the dehydration study to your doctor. My doctor tells me fasting isn't required anymore since about 2012 or so.

https://www.statnews.com/2016/04/29/...terol-testing/
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