I am on 300 mg Welbutrin XL (the generic alternative) and along with therapy, I think it took a few weeks before I really started feeling much better. I did notice more energy fairly quickly, though, and got back into jogging (which I was doing pre-pregnancy). Now, my mood is much more even, and between the meds and my weight loss, I have a LOT more energy to keep up with my 10 month old.

I've been on 300 mg of Wellbutrin for about 5 months now. I did start out on 150. Unfortunately I haven't noticed a difference on it. I'm also on 300mg of lamictal and 10 mg. of abilify. The trio cocktail is supposed to help my mood disorder and depression. However, I'm usually in a general state of ambivalence. My mood disorder isn't quite as bad and neither is the depression. But I also don't have that wonderful boost of energy that other people have experienced. Sometimes I wonder if my dose isn't high enough or if my tolerance for medications is too high due to my weight. But in general I haven't noticed any benefit or detriment to my physical / mental state. I have to say that I am extremely jealous of those who do receive the energy boost / weight loss from wellbutrin. I hope that I can be jealous of you too because it means that it's working for you. :-) Good luck!

I'm taking Wellbutrin XL, I'm not taking it for depression issues, more for controlling an eating disorder (it's the only reason I've managed to lose weight. I'm down 25ish pounds since the beginning of June). The only side effects I've had are insomnia, some emotional problems initially and a persistent ringing in my ears. The ringing in the ears drives me nuts sometimes but it's a well worth trade off to feel better, IMO.

Hi! Wellbutrin is actually more keyed to weight-loss. It is often one of its side effects, along with diminished appetite. I really liked Wellbutrin until I experienced severe Hyponatremia from it (almost unheard of with Wellbutrin), was subsequently hospitalized, and obviously immediately had to stop taking it. For what its worth, I really felt better on it. Don't take it late in the day--it will keep you up. I highly recommend integrating some behavior activation (a form of cbt or cognitive behavioral therapy) which has been found to be extremely effective in numerous double-blind studies. It pretty much involves getting out and doing something-any activity. This empowers the person, keeps you from being isolated etc. Often times you don't feel like doing anything or feel any joy when you are depressed. They often ask you, "if you weren't depressed, what would you have been doing", or "what activities did you used to enjoy". You then complete them, and rate them. It can be as small as going to a movie, an exercise class, window shopping, going to a book store etc. Just getting out and doing something-- makes you feel like you have some control over your life, and like you accomplished something. Good luck, and I hope you are feeling fantastic again soon!

I think its been two weeks now...Still nothing... went to the doc. They're talking about upping it to 300 in a few weeks.