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One of the scary but true potential side-effects of overusing aspartame is the connection with a specific type of tumor (pituitary, I believe, if I'm remembering correctly).
These tumors aren't due to the aspartame itself, but to the fact that aspartame in very large quantities can deplete folic acid (other foods can do this too. In fact, many of the foods that are "enriched" with folic acid are also foods that can deplete folic acid - which is why the folic acid is added into these foods). So, if you're not getting enough folic acid (by eating plenty of plant foods), drinking diet sodas and other foods containing aspartame is going to worsen a folic acid deficiency or put you at risk for one (and increase the risk of these tumors).
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I believe it. My grandmother was an avid diet coke drinker. Tons of pops a day. Then, she was diagnosed with a brain tumor. I remember my mother was saying it was because of the diet cokes but I don't know if that was ever doctor agreed on. Either way, a few years after, I started to have massive migranes, dizzy spells and other symptoms as a twelve year old. For some reason, we took out the diet sodas I lived on and they got better.
There are tons of foods that have aspartame in it.
I was eating Fiber one cereal and started to have headaches. I never connected the two and one day I happened to look. Bang! Aspartame in it. I've had arguments with people at restaurants because I just want to know what makes this dessert sugar free and they don't know/care. I just know that aspartame does not agree with my body.