I know it's sort of pointless to say that one has proof of whether or not sugar subs are toxic or not.
most holistic sources will say they are detrimental to your body, then the next article you find will be a study saying that there was never any risk after all.
So in the end you just have to make your own choice.
but here's an article that's pretty comprehensive of all the sweetners.
http://www.mvholisticretreat.com/art...l/sweet-poison
another thing to think about, and the source of this is completely from my own brain, but the whole reason for consuming something is so that our bodies can break it down and use those substances to nourish and rebuild tissues and cells. So ideally when a person eats something, the body would want it to be vitamins and minerals that it can absorb into its tissues having a positive effect on the organism as a whole.
when chemicals or substances that cannot be used to rebuild tissues and cells are introduced into the body, they will interfere with what really needs to be done. they can either lodge into places blocking real nutrients from doing their jobs, or they can accumulate in tissues because the body doesn't know what to do with them. and anything foreign in the body is going to cause an immune responce, which could result in inflammation, aches and pains and other toxic conditions over time.
Strain is also put on the body to rid it of these useless substances. The liver and kidneys are doing extra work to clear them from the system. Energy, vitamins and minerals are used in breaking down these substances which give nothing back in return. So it becomes an extra stress to the system.
So this in a nutshell is what is behind my descision not to use artificial sweetners and sugar on a regular basis.
and i'm by no means perfect in avoiding sweet stuff. And by the way i also believe it's addictive, but i wont go into that
but I do try to avoid it and i don't believe any of it is safe or benign.
I think we also should try to remember that we may not feel bad right away after consuming one of these sugar substitutes, but that does not mean that over time, there might not be chronic effects occurring in the body, and many of these substances have not even been around long enough to be able to determine what effects they can have on a person who has consumed them for a lifetime.
I hope this doesn't come off as 'doom and gloomy'. i just want share my thoughts and feelings on the subject. of course it isn't scientific, but it's the cumulative judgement i've made based on all the articles i've read jumbled with my own gut feelings.