An article from the BBC News entitled "Obesity gene 'affects appetite' " about a study that is also published in the Journal of Clinical Endocrinology & Metabolism.
http://news.bbc.co.uk/2/hi/health/7525347.stm
Wow! This makes me wonder... I believe that both genetics and environment can play a large role in weight. Looking at my Mom's side of the family especially, where of 8 children, 6 have struggled with their weight and range from overweight to obese, I would guess that if there are "obesity genes", my family carries some of them. I've always felt is that I just don't seem to have that "off" switch when I'm eating - I can just eat and eat and eat and it's not until I've grossly overeaten that I feel full. I've really had to teach myself what a portion size is, and usually eat now just so that I don't feel hungry anymore.
What does everyone else think?