My macronutrient goals are to get 30% of my calories from protein, 50% from fat, and 20% from carbs. This works out to just over 100 grams each of fat and carbs, and 150 grams of protein for me.
The amount of protein you need is supposedly based on your lean mass, so it helps to have an idea of your body fat percentage. I have about 140 lb of lean mass, so 140 grams of fat would be a good/high target (1 gram per pound of lean mass is what most bodybuilders aim for I think). 300 grams sounds like way too much.
I'm on high protein because I'm trying not to lose too much lean mass while I lose weight, which is especially difficult for women (my understanding is that testosterone helps you hold onto lean mass, which may explain why women have more difficulty losing weight as well). I'm not working out, but I'm relatively active.
I should note that while my goals are set per above, I have yet to actually hit my protein target in a day. I've gotten close but 150 grams is a LOT of chicken and fish to put in a day of food for me. It's easier to look at it as a percentage for me, and try and make sure I'm as close to 30% as possible... if I drop below 20% I make an effort to have more at dinner.
I don't worry about where my protein is coming from (plant vs. animal). Instead I eat the things I want to eat that fall under the whole/real foods umbrella. Usually I prefer meat over beans and tofu, so I eat meat. I eat red meat just as much as chicken. ...yeah, I eat what I want. I'm tired of the medical profession changing its mind about everything. Now apparently red meat is good for you again, but even if it wasn't I'd just eat it. It's a whole food. It fits in my plan.
Do I sound bitter?