I've read that the non flushing type niacin is not as effective and may be harmful to your liver. I've been taking the flushing niacin for several months and it has helped. My cholesterol did go down a little, but I haven't had it checked recently. My blood pressure is lower, too. But it could be from eating better, too. I think it has increased my circulation. My hands were falling asleep at night, but that has stopped. I did turn red when I started using it. If you take it with a meal and start at a low dose like 50 mg, it will help prevent the flushing. I like the flush. It makes me feel like its working.