I've been using Xenical faithfully for the last 2 1/2 months and I've already lost 20 pounds. The weight isn't so important to me but the change in size is. I've gone from almost a 16 to a very comfortable size 10 and it hasn't stopped yet! It was actually the only weight loss medication my doctor would prescribe because it doesn't affect your metabolism or your mind so it's not hard for you to keep the weight off when you stop using the pills. My insurance covered it based on my BMI alone and that was wonderful. The best advise I can give if you decide to try it is don't cheat! You'll be miserable if you do. The lower fat, the easier it is. I'm getting married in August so my motivation has been picturing myself in a wedding dress - ack!