I just went to that website, and I gotta tell ya that just the fact that the manufacturers/marketers of Estrin-D also market the diet scam pill Leptoprin would be enough for me to keep my Visa card in my wallet.
It amazes me how all the diet pill folks are trumpeting that their product "CONTAINS ABSOLUTELY NO EPHEDRA!!!" as if they were omitting it out of the goodness of their hearts and not because the FDA has banned the substance. Oi.
I'm not menopausal yet, but you might consider going to an endocrinologist - a close acquaintance of mine at work has been seeing one and has lost a great deal of the weight she gained during and after menopause. I believe he put her on some prescriptions (not sure which ones) and she's on a low-carb diet.