I've been taking a D3 vitamin. I haven't really seen any changes yet, but it's more for preserving my bone health for later in life, and perhaps as I take it longer it will help with energy.
Most vitamins should be taken with a meal, or else your body won't receive them as well. In general, multivitamins are not absorbed as well as the natural vitamins in food, but since I am so deficient in Vitamin D (living in the northeast, wearing lots of sunscreen because I burn easily, and generally not being outside a whole lot, I don't get very much), I think that some is better than nothing!
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