I would not worry about it if it is your calve muscles and not your ankle joints.
I often get sore calves if: i) I am running hills; or ii) I am bouncing along on the balls of my feet.
I can also get sore ankle joints with these as well, which is a more serious issue.
To fix sore calves, I would make sure you stretch well after a run. And I swear by fish oil (or eating oily fish) which helps reduce inflammation and lowers recovery time (at least for me and I run daily).
It's OK to end a run with sore calves but unpleasant to start a run with them.
If you get them mid-run, I find slowing down helps as does trying to run more "flat-footed".
Last edited by IanG : 09-19-2014 at 11:47 AM.