I tried the generic form, not sure if that's Leptoprin or Leptopril. Anyway, I tried it for at least 2 months, I did lose some weight, but it came right back when I stopped taking it. I think maybe it helped flush out some water. The only side effect I had was a little constipation. My exercise of choice is walking, so I did walk at lease 3 times a week. I cut back my portion but still pretty much ate what I had a taste for. Started low fat, low cal., low SODIUM! diet on 9/27/05, so far I've lost 45 lbs. I have a long way to go, but I'll get there.