From their website:
BioLean LipoTrim™ is a highly active, synergistic combination of garcinia cambogia extract and chromium polynicotinate.
Garcinia, or Hydroxycitric Acid (HCA), is commonly sold as a weight loss supplement. It is available alone, but is usually sold in a combination pill that includes other supplements such as ephedra or chromium. It is often sold as CitriMax or CitraLean. It is claimed to reduce appetite, burn fat, or prevent the formation of fat.
Studies on animals suggested that HCA might affect the way the body burns carbohydrates and stores fat. However, no studies have shown similar effects on humans. An extensive study by JAMA concluded: Garcinia cambogia failed to produce significant weight loss and fat mass loss beyond that observed with placebo.
Is HCA safe? According to Berkeley Wellness: no one knows if HCA has any long-term adverse effects; some animal research found that it's toxic. It may be combined with other diet compounds, and the safety of such products—witch's brews of herbs and chemicals—is certainly questionable. The PDR for Nutritional Supplements states that pregnant or nursing mothers, and those with dementia syndromes such as Alzheimer's disease should avoid HCA. They also state that those with diabetes should be cautious with it.
There is no evidence to show that HCA is beneficial for weight loss, and it can be harmful in some cases. It is better to wait and see what future research shows before taking it.
Chromium is believed to be an essential trace mineral. One form, chromium picolinate, has been sold as a weight loss aid for many years. It is claimed to boost athletic performance, build muscle, and promote weight loss. The Federal Trade Commission have determined these claims to be deceptive.
While chromium may have health benefits, extensive clinical trials have shown that chromium does not have an effect on weight loss. Chromium can cause side effects in many people, including everything from stomach discomfort to genetic mutations in DNA. Chromium may also interfere with other supplements or medications.