Hi all--I am new to the board and have read through many posts about how taking meds and losing weight just doesn't seem to jive at times. I have been on meds for depression for years and although my mood has been stabilized, my weight has climbed excessively through the years. I can lose some weight if I stop taking a med or two (I take three), but my mental state suffers. I have been over this with my doctor on numerous occasions and she calls my meds "weight gainers". I try to combat the depression but it gets worse when I look in the mirror at how huge I am and when you're short it's awful. I have dieted, joined a weight support group, exercised or just walked and nothing helps. The support group I belonged to had people in it who only had to lose 5-15 pounds at best so they don't understand how I feel. I need to lose roughly 100 pounds and I feel it's never going to happen at this stage. I would love to hear from anyone in a similar situation. Thanks so much!