Hey Tigerlily, I was actually on Celexa for a good amount of time, and I did gain weight on it. I read this interesting article that said sometimes a person's Serotonin receptors do tell the body it has reached Satiety, and that can be something that leads to weight loss. After time has passed, though, I guess I had some of those effects less, and most SSRI's (and Effexor) can cause you to crave carbohydrates because you feel less satisfied.
Thanks for your response Tohisha! At the time of first going on Effexor XR my then-Psychiatrist did say most people lose weight on it. It does depend on the individual's biochemistry though. With this drug I did seem to have an initial weight loss in the beginning like with Zoloft, but then it caused me to crave more carbohydrates more than anything (which can somewhat be controlled) and over months I kept on gaining weight, which led to a total gain of 45 pounds. Like over 30 lbs was during the Effexor, but throughout that experience it was augmented with Remeron (gained 10 lbs on this), and last year Abilify, and then Wellbutrin.
It could have possibly started working better if your dose was raised, but I myself am looking for more natural ways, and might even get down to my high school weight!
These drugs definitely affect how you eat in most cases I think, because before even going on depressants I mostly ate less when being depressed.
Good Luck to you all.