Yes, I was on Effexor XR and gained 30 lbs. over one summer. Granted, I was still somewhat depressed and was eating a lot, but I'd never experienced weight gain that rapidly. I'm now on a combo of Lexapro and Wellbutrin and it's been weight neutral. However, changing antidepressants is a big decision, so you should probably talk to your doctor about your options. And not a primary care physician, but a psychiatrist who can try to modify your medications to have fewer side effects.
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1st mini goal: 249
2nd mini goal: 224
3rd mini goal: 190
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