I have been on prozac for two years, then cymbalta for another two, with on and off in between. Prozac made me anorexic, I just could not eat on it. I also felt like I was on extasis, the drug, too "happy" and talkative. Cymbalta is a lot more natural to me, stabilizes my mood and I feel a lot sadder, but more "real". Anyway, try yourself, not everyone is the same, also tell your doctor how it's working for you. He's the one you should be asking, not us