I use EA Sports Active and Wii Fit and they both can give you a total body workout. They are quite different in that Wii Fit doesn't set up a program...you have to queue up each exercise. But Wii Fit offers a yoga portion which is a great asset.
EA Active runs you through a workout. I did find core work a little lacking but the last 2 workouts I did have improved on that. Other ladies on this board have used Wii Fit much more extensively than I have so I am sure they have better input on it.
I have (but haven't yet tried My Fitness Coach but I did use the PC version of Yourself Fitness (same thing as far as I can tell) and it was great. Full workout in a program format.
I have been working out with a trainer to get me jumpstarted back into fitness as it's been a few years (and a few children) since I have really exercised with any regularity so I am finding it an adjustment to do the "game" workouts. I think as long as I am up moving and sweating and putting in 100% effort I can't go wrong
I did my workout for yesterday int he evening which was a change for me. I really enjoyed it though and slept like a log! Maybe evenings will be okay for me after all.