I'm in the middle of Lustig's Fat Chance in which he describes the anatomical regions of the reward center in the brain. I wonder if real time brain imaging could shed light on the effects of these sweeteners, maybe with sugar as a control. Really interesting stuff to wrap our minds around, if technical.
Back to sucralose: I don't find that the individual Splenda packets to be that sweet, not compared to IP Strawberry wafers & fruit drinks, Mio, and especially compared to Muscle Milk. Maybe it's dose related or there are other sweeteners adding to the effect. Time to re-read labels. Addiction to sweetness....wow.