Watching calories helped me lose 100 pounds two years ago, and keep it off since then. However, while watching calories it was essential to make sure I was getting complete nutrition: Enough protein (at least 60gm, preferably a lot more), enough fat (fingernails and hair are good indicators -- as long as they're okay, then you're getting more than enough fat), and especially vitamins and minerals (at least 3-4 cups of vegetables and fruit per day). That kept me healthy all the way through, and even since entering maintenance.
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