As you can tell by the name i've chosen for this forum, Sugarhabit, a sweet tooth is my main downfall and always has been with trying to lose weight. So, of course, when trying to lose weight in the past, and not really being ready to give up the sugar taste, I replaced my dependence on sugar with a dependence on artificial sweeteners. I couldn't get through a day with a couple of cans of diet soda.
Anyway, I don't claim to know whether the artificial sweetener tricks my body into believing it's getting real sugar and thus not dropping weight or anything like that BUT I can with complete certainty tell you that having all that artificially sweetened stuff, especially diet soda, meant that my sweet tooth never diminished and therefore I kept craving sweets and sabotaging my diet and often, making weight loss nearly impossible.
It was only after I decided that I needed to ween myself off of the sweet stuff and chased it mainly in things like fruit, was I able to curb my cravings for sweets significantly and was able to lose weight.
I hope that helps?