Having been diagnosed 3 yrs. ago as permanently disabled due to my liver disease, I feel like I've lived on both sides of this coin. Yes, I lost the weight . It was actually killing me. I still live with the liver disease, but I'm much healthier now than I was then. I am happier. I'm able to physically do more and mentally handle more.
I would choose a permanent disability over being obese again. That may seem selfish to some, but at my previous wt. and in my previous health status, I wasn't living, I was waiting to DIE.
OTOH, if I were a reasonably healthy person and my obesity was the only factor that I was considering, I might choose differently.