Not sure what your exercise regimen is, but it's great to shoot for 5-6 days of cardio and at least 3 of weight training. When I'm not injured (as I currently am, dang it), I do 6 days of cardio and 6 days of weights. With that said, do as much as you can without burning out--that's the main thing. Personally, I do think it's beneficial to take at least one day off and engage in active rest (i.e., go for a walk or do something relatively active that isn't in your usual routine) or, hey, just veg out and enjoy your couch. At some point, most people really will crave exercise.
Questions are good.